Autonomous vehicles will be here soon and will cause major changes when they arrive, similar to the building of the Interstates in the 1950s. AVs will bring safety, ease congestion, and provide mobility for many people who now find it difficult to travel. They will also erase many jobs, erode highway funding, and take customers from public transportation. For geospatial professionals, AVs will mean great opportunities in mapping, routing, site location, advertising, land use changes, and other areas. This Forum provides a look ahead to the US with AVs and will describe how we need to prepare.